What powder can you get locally in good supply? start with that. My normal load is a 130gn bullet, Federal Mag primer, 58gn Re22. As re22 is getting tricky to find, I am experimenting with Elcho 17. Over the years, I have used Gamekings, Prohunters, Interlocks, and Interbonds. All work fine.
The best advice I can give you is, Keep a detailed diary of any load development that you do. Because I kept all the records from when I was working up loads, I had several usable loads that I new were safe and accurate in my rifle. When I couldn't get gamekings, I swapped to Interlocks but already new what load I needed. .270 seems to be very forgiving. If you can get a copy of the article Jack o'connor wrote about .270 load development in Pet loads some years ago, it is a great read.
Don't get too caught up on components, the majority will work fine, don't try and be to clever and stay within the recommended loads in your data. Have fun
Ezzy