Interested in your experiences
I used to have a 308 but had a Sikka stag run after the bullet went through both lungs, one kidney & lodged under the skin of the contralateral flank. It ran 200 m downhill then 200 m into forestry. I found it in the morning after a fretful night.
I thus changed to a 25-06 which was flat shooting and did drop them on the spot but was very destructive in terms of edible meat. It was horrible to shoot without a moderator & even managed to smash the windscreen of my 4x4 by firing off the bonnet.
I thus choose the middle ground with a 6.5x55
I understand bullets kill quickly by sending a hydraulic shock wave via the blood to vital centers of the hindbrain. The brain can auto regulate minor changes in Blood Pressure but a bullet strike is like a JCB, with its ram half extended running into something with its bucket, this peaks the Hydraulic pressure. Studies with pigs shot in the haunch show that they stroke out with a pressure wave in the brain.
If you shot a deer with a musket ball through the lungs, it will die, as the oxygen levels to its brain fall but you will not get a 'drop on the spot' as there is no high velocity pressure wave.
What are your experiences please?