We have a problem with Asian Water Buffalo in Australia. They were originally imported here as a food source in the early days in the Top End of Australia. They ended up going feral and became a huge pest (no pun intended) They can be extremely unpredictable and do a lot of damage on the flood plains of Northern Australia. I live a lot further south than that, but a local farmer decided to bring some down here and farm them for meat, which is very good and lean. Then rather predicably they went feral and set about pushing down fences and generally being a problem. We were asked to go out and cull them, but the problem was the sort of terrain they live in. It's very close thick scrub that a dog couldn't bark in, and you seldom get them out in the open. Also we get a lot of rain here, and that makes access almost impossible at times. It's an ongoing job in progress. Here's one a shot with a 308 with a 165gn Hornady.