It's as much an art as it is science. Putting together one of my favorite loads for the 30/06, 61 gr RL 19, Fed 210, Sierra 150 gr. pro hunter. This load is usually a tack driver, today, I can't get it to group worth a dam. The only component change is the case, I usually use Remington, today I used the Nosler brass that I had prepped.
On a positive note, I found an excellent load for my son's 7/08 using H4350, as suggested by Miur. 42.8 gr (1 scoop of the Lee 3.1 dipper) of H4350 and a Nosler 140 gr. partition. , Fed 210, Norma brass. That is not the max load but it will give it plenty of juice to take a cow elk at the ranges he will be shooting. Rifle was a Vanguard youth model, 3 shots touching at 100 yards. For the money, the Vanguard is a good rifle.
Back to the bench for the 06 load.