I cannot comment on this as I have not used a .22cf for deer. However i have been out with a chap in Scotland when he used his .222 and it stopped roe perfectly and with little damage, I believe he used factory 55gn ammo. However there was another chap on the estate who was using a 22-250 with his patent home-loads and his roe carcass's told a different story.
Now my question is this do you think the higher velocity .22cf's like the 22-250 leave more blood blistering on the exit side of the carcass to the more moderate velocity .22cf's like the .222, or was this just an anomaly?
Simon