I regularly stalk deer in Scotland and have also stalked in other countries for deer, elk, bear.
I have used rifles in various calbres e.g. 6.5x55, 8x57, 6mm Rem., 7x57, 6.5-06, .308W., 338-06.
I really have no particular preferences when it comes to rifles or calibres as I think bullet construction is most important of all.
I am 68 years old and feel I need a light rifle now. Have purchased a Baikal Iz-18 in 308W and want to give it a try.