Musty,
I use a uniformer once on new brass, after that i just clean the pocket in the usuall way. All new cases are full length resized, checked for length, flash hole de burred, primer pocket uniformed, case neck's de burred then chamfered (that way round).
It might not make a huge difference but the tools aren't expensive and it certainly wont hurt.
Remember that a pocket uniformer only cuts the bottom of the primer pocket so it should only cut once anyway, after that you would just be cleaning the pocket not removing brass.
Ezzy