I set my 22mag 1" high at 100 yards. Depending on the ammo you use, you should be then zeroed at 120-130yards and 3-4" low at 150 yards.
120 - 130 yards is the realistic maximum range of a 22mag. That said, the 30 and 32gr ballistic tip type ammo has made the wmr a much more useful round than it was with 40gr HP ammo.