I haven't used the 7x64 but I have built and shot a half-dozen or more rifles in 280 Remington which is a very similar cartridge. Most of these rifles were for customers in New Mexico who used them on mule deer, antelope and elk. Nothing but praise for the cartridge and it's performance. Since the 7x64 has only the slightest bit less case capacity than the 280, I'm sure it will perform similarly.~Muir