Results 1 to 5 of 5

Thread: Pexion as an alternative to Epiphen

  1. #1

    Pexion as an alternative to Epiphen

    Chaps, does anyone have any experience of Pexion for an epileptic dog?

    My terrier has been on Epiphen since October last year and has been doing really well - frequency of seizures has reduced hugely from one quite severe 30min plus seizure approximately every 3 weeks to one minor 5 minute one in January and a similar short one last Friday night (and I think the trigger for that was processed pork as he had a sausage which he is not normally allowed).

    Last time he had his bloods done the vet said he was at the low end of the levels so I said if he fits again we will look at increasing it. He went to the vets today for bloods and then to increase the dose but my mrs has called to say that they have not done either of these things but have suggested Pexion as an alternative with less side effects in the long term.

    I have briefly looked up this new drug (I studied medicine for 3 years so wanted to look up the pharmacology but can't find it) and it appears to have only been licensed for 3 months.

    I am reluctanct to change when we have a solution which is working very well unless I need to ie unless it is causing liver function issues (dog will be 4 in August) and put him through the side effects associated with starting a new drug.

    Any advice or experience would be very much appreciated.

    Anthony

  2. #2
    All i can say is that our bitch has been on epiphen since she was 5, she is now 11 with no further episodes and no side effects. She is very active and does a full season picking up 3-4 days a week every year with no problems. If you aren't having any issues with epiphen I would be very tempted to stick with it especially if the other drug is new on the market.

  3. #3
    My thoughts exactly - although he has had two very minor episodes in 10 months it is a huge improvement and I don't want to risk something with less pedigree so to speak and possibly less efficacy.

  4. #4
    Have a chat to your vet about why they are thinking of swapping? In a stable dog then I'd be reluctant to swap therapy, but there could be other reasons - serious changes in liver enzymes would be a reason to look for alternatives.

    Section 161 of the Highways Act 1980 (England & Wales) makes it an offence to discharge a firearm within 50 ft of the centre of a highway with vehicular rights without lawful authority or excuse, if as a result a user of the highway is injured, interrupted or endangered.

  5. #5
    Quote Originally Posted by Apache View Post
    Have a chat to your vet about why they are thinking of swapping? In a stable dog then I'd be reluctant to swap therapy, but there could be other reasons - serious changes in liver enzymes would be a reason to look for alternatives.
    Exactly my thinking, I wasn't there and the mrs was...they haven't done the bloods yet so the suggestion was not based on any clinical signs or results...just that we asked for the dosage to increased because the last bloods indicated that blood levels were at the bottom of the range. Phenobarbital is clearly working because the frequency of episodes is so dramatically reduced so unless the bloods which are being done tomorrow show liver issues I don't see a need to change.

    Being probably overly conservative, I am not keen on putting him on something which has only been licensed for 3 months as far as I can understand in place of a tried and tested drug which is working well.

    Thank you for the advice.

    ​Anthony

Similar Threads

  1. BASC alternative
    By MJ75 in forum Deer Stalking General
    Replies: 156
    Last Post: 03-09-2012, 20:29
  2. NV alternative
    By simon t in forum Equipment & Accessories
    Replies: 21
    Last Post: 24-01-2012, 22:37
  3. Heads up on alternative
    By Mannlicher_Stu in forum Equipment & Accessories
    Replies: 0
    Last Post: 30-11-2010, 16:54
  4. VARGET alternative???
    By nell in forum Ammunition, Reloading & Ballistics
    Replies: 21
    Last Post: 28-07-2010, 22:12
  5. venison alternative!!
    By duggers in forum Carcass Prep, Butchery & Recipes
    Replies: 5
    Last Post: 15-05-2008, 21:29

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •