I use the RWS 100gn in my 243 and it works very well, albeit they do tend to run a bit with behind shoulder shots. I know several stalkers who use 75gn and 80gn softpoints on Roe and it seems to drop them on the spot. If you can get them at cost and they shoot well in your rifle - ie into abusiness card at 100 metres (they don't need to clover leaf) then go for it. If however they are 75gn HP load - that is more of a varmint bullet that will fragment and expand very quickly. If you are confident enough for head and neck shots they will work well, but make quite a mess, but I would be cautious of body shots - behind the shoulder through ribs probably OK, but not on the shoulder - might not penetrate to the vitals and lot of mess.