This may help, from Nathan Fosters site
Barnes bullets include the 130, 150, 165, 168, 180 and 200 grain TSX bullets along with the 150, 165 and 180 grain MRX bullets (MRX untested here).
The Barnes 130 grain TSX is a good all-round bullet for game weighing up to 150kg. It is highly recommended that readers wishing to experiment with the Barnes 30 caliber bullets for use on Deer, experiment with this projectile. Meat damage is as per usual minimal, regardless of violent internal wounding. The TSX really is a good meat retrieval bullet, proving useful in the .30-06 out to ranges of around 400 yards.
The 150 grain TSX bullet is best suited to game weighing between 90 and 150kg (200-330lb) and is adequate for use on heavier bodied deer up to 320kg (700lb). Wounding is at its most violent at impact velocities above 2400fps on lean game, displaying hydrostatic shock above 2600fps, as is the norm with .30 caliber bullets.
The 165 and 168 grain TSX bullets are best suited to large, heavily muscled game weighing above 90kg (200lb) and up to 320kg (700lb). The 180 grain Barnes is much the same, requiring heavy resistance, not to aid expansion, but to ensure adequate energy transfer. These are clean killing, deep penetrating projectiles but delayed killing can and does occur at impact velocities below 2400fps. The 180 grain TSX does its best work on game weighing between 320 and 400kg (700-880lb), producing excellent penetration on game weighing up to and above 600kg, but cannot, due to its bore diameter, be expected to render wide internal wounds on such heavy game.