Yes.
How and why they vary I cannot tell you. Prion proteins are normal parts of cell function - many speculated roles. The disease prions are mis-folded ones, why, I'm not sure. The nuisance is that as most means of disinfection involves changing a protein's shape (heat, chemicals) the fact that they are already misfolded makes it hard to remove them properly. Why some remain in the nervous tissue (BSE) and others get excreted I really can't tell you - it's a level of cell biology currently beyond my ken (and time, frankly, I'm concentrating on other complex areas like reloading...)
The animal requires copper in trace form for the prions to function normally; where this is absent or prevented from uptake, by eg use of organophosphate based pour ons ( administered along the spine and getting into the spinal cord, as one may observe) and where the copper molecule is replaced by a molybdenum one, the misfiolding occurs.
Disclaimer, I’m not a vet, though neither was Mark Purdy, the small scale farmer who researched this aspect a little and brought it to the attention of others. It’s a chemical world. Proteins in chicken food are often derived from dead chickens, same with cattle supplemental food at the time of the outbreak, more greed than anything. In NE Scotland the grass grows so fast in summer the cattle cannot keep up, but the oft show example of BSE infected and distressed animal was one of a dairy cow ( high density) living on relatively intensively cropped grazing ( Devon small acreage dairy unit) which was mature (- had several years of pour on administered) and was fed on supplemental rations (made with knackered old other stock of similar type and fed toxic feed whilst being poured on every year too). The means of the body dealing with such persistent toxins is to encapsulate them in fat


(it’s of course all ‘muscle’ on yourself, I know

), these fats were stripped from the carcasses and sent to the feed producers, and of course not sufficiently sterilised (an impossibility, given the knowledge that prions can persist even on autoclaved surgical instruments) and the feed them given to the cattle. No means of any mature animal avoiding a double or multiple dose of the organophosphate poison.
The classic symptoms associated with organophosphate poisoning/overdosage in all mammals is spongiform encephalopathy.
CWD has been found in Scandinavian reindeer herds also. The link is likely as not to being the supplementary food ration (which comes in a bag and off a pallet as opposed to in a bale from a field) offered, as any natural cause pathway.
Deer in many highland estates are fed silage and chopped neep or bulk carrots, but tend not to get fed from bags from feed manufacturers.
A neighbour of old and since passed used to be a rep for a major UK animal feed manufacturer.
We reap what we sow.