That’s my challenge with long range shooting, no matter what you use velocities and energy drop away as you get down range. Most would say that a 22 hornet is very marginal on deer even at close range, but by the time you are out to 5 or 600 yards the energy and velocities are down to those sorts of levels. Shot placement is everything, but at those sorts of range natural dispersion of a bullet, wind and minor errors in range estimation and drop or windage compensation can easily take bullet off the vitals. And no bullet, whatever its made from, will the energy to set up a wide shock wave to do organ / blood vessel damage much beyond the path of the bullet.
In other words, at normal ranges the shock wave will mean organs, nerves and blood vessels will damaged both directly by the bullet and by the shock wave - temporary wound cavity which is three or four inches either side. But impact at 600 yards your wound cavity will only be slightly bigger than the diameter of the expanded bullet.
Take an accurate rifle with a good shooter behind it in perfect conditions. It will do a 2cm group at 100. More likely with 10 shots group size will be more 4cm. That’s the natural variability.
Move out to 600, a 2 cm group is now 12cm, a 4cm group is 24cm. Assume your point of aim is middle of vitals, just natural variation in grouping can put your bullet 6 to 12 cm away from point of aim. That’s with perfect conditions, no wind drift, no drop mistakes etc. And flight of bullet a few tenths of a second. An animal can easily move quite a bit during time of flight. And at impact velocities of sub 2,000 fps and 1,000 ft lbs of energy expansion and shock wave is much less than at 2,500fps and 2,000 + ft lbs which you have at 200 yards or metres with most cartridges.