In handling you wont notice the difference between the 222 and 223. Both calibres are proven on fox / vermin and are deadly accurate. Both share similar running costs as well as recoil and noise qualities.
Having used both - For me the 223 is the better option - it simply shoots flatter , is less affected by the wind , and hits harder. There are more choices of rifles available and more barrel twist options that allows the 223 shooter to use a range of bullets that the slower 222 twist barrels cant. - This makes the 223 far more versatile.
If you ever wish to sell the 223 - it will probably fetch a higher price in the second hand market or as a px, as they are far more popular.
The problem for the treble is that its main rivals - Similar sweet shooting foxing and vermin calibres such as the 223 - 20 cals and the 17 rem / FB are better ballistically by margin.
ATB
Alan