The 150 with front end intact shuld penetrate "enough"Very fast monolithic bullet will shed the front part (petals). This will actually help with penetration, but the damage/cavity might not be in the ideal place.
Not directed at your post, but I get tired when people talk about monolithic weight retention and draw a conclusion it must mean excellent penetration. And also go down in bullet weight. It's a tried and true recipe from decades ago, that bullet frontal area hinders the penetration.
A double diameter bullet has 4x frontal area compared to non-expanding (or one that lost the petals). Let's say we have a 150gr bullet (easier math) and front/petals weigh 50gr. Do you expect a fully mushroomed 150gr bullet (4x frontal area) or one that loses the petals, weighs 100gr but has original 1x frontal area to penetrate better...
The high velocity is responsible for the temporary cavity.
Why not drop weight slightly, same length (so twist is fine) and weights retention means you don't need to acccount for lost weight.