Hello HS.
Yes you can, although some will say that the moderator bore linked to the size of the bullet fires has better attenuation. Personally, on my .243, and .30-06, I use .30 Cal mods... The .243 is not much quieter with a .25 cal mod as I tried it, but did not get good accuracy, so went to a .30 cal Roedale, and things improved immediately. Not a scientific answer, but only my experience.
All the best.
Neil.