To be fair, I'd be trying to get 110gr to go pretty fast, just for flatness and down-range energy rather than anything else. It would get a bit loopy if run much slower, and the load look far from too much.
It makes more sense now we know the MV is 3275fps, rather than the eye-watering 3740fps in the OP - though I think I'd just set it about 2" high at 100yds for a zero at about 250yds - and then hold over a bit for 300yds.
It would save a lot of twiddling: but I guess it depends how big your target is.