Consistency is the goal. Taking into consideration BH's comments about 'comparison', we can get a better idea about what's going on by 'sidestepping' to something that is much easier to see.
Imagine a rifle with open sights that shoots nice tight groups, but they are always 2" high and 3" left of point-of-aim (POA). Because we KNOW that the center of our groups (the point-of-impact (POI)) is always 2" high and 3" left, (the "bias"), we can compensate (correct) for the bias by aiming 2" low and 3" right of where we want the POI to be.
In the case of cartridge lengths, assuming the Comparator is the exact same diameter as the bore (when it isn't), introduces some
unknown level of bias into the settings that we use for seating depth. Our settings will be
consistent, but they MAY be biased (and likely are). Without
measuring we can't know what that bias is. If our settings,
with their bias, "work", then measuring every bullet isn't necessary, and having the inside diameter of the Comparator be
exactly equal to the bore diameter isn't necessary. This is precisely why I said, process isn't as important as results. However, if we
eliminate the bias in our chamber measurements, we are doing the equivalent of adding a 'scope to the rifle in the above example, and we can 'adjust' the sights so that the center of our groups are coincident with the POA.
It isn't difficult to make the ID of one's Comparator equal to the bore of your rifle. It only requires slugging your breech, and using a little emery paper and a dowel on the ID of your Comparator. (In my experience, most Comparators are "small" relative to the true bore.)
BH is a machinist. His life is precision and accuracy. He has "issues" with "bias".
Regards,
Paul