This. Lyman made a case for KAPOK fillers to hold the powder against the flash hole to avoid this. Unfortunately, cast bullet competition shooters using this found that they would get a ring/bulge in their chamber necks. "Grex" granulated shotgun buffer was used but I never followed the results.What I have seen, is inconsistent burns in such loads. So I use case fillers not to reduce empty space, but to hold the charge in a repeatable position against the flash hole.
There is a warning to be had about small charges of quick burning shotgun powder such as Red Dot and Green Dot listed in the Lyman manual if you look, they often generate jacketed bullet pressures in the 45K class delivering puny velocities. It's a great illustration as to how pressure and velocity are not in lock step with each other. It is very possible to get high pressure with very low velocity.~Muir