Ivermectin, for the interested

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And as for protecting others again i just don't get it, from my basic laymens understanding of this virus most of the problem with it is so many folk are asyptomatic with it so spreading it unwittingly, if the vaccine still allows u to catch and spread it i'd imagine the chances of u being asympotmatic are even higher so ur more likely to spread it. to others as it lessens the viruses effects.
Don’t forget that there is aye the option to do as the dear old biddys in Toronto, Fairy Hill’s headhunters in PNG, the people of Uttar Pradesh and the frontline health workers in Buenos Aires did, and elect not to risk getting the virus in the first place, whether by accident or purposely, but in either case with the use of ivermectin. If the virus isn’t in ye, you canna spread it, hence the very low incidence of daily cases where it is in widespread use, the virus needs people to breed in and pass on. The vaccines, alas, cannot prevent this, indeed they facilitate it, by dint of giving folk a false sense of security.
 
I think you make a good point here. I think you can also factor in wide variations in reporting (of confirmed cases and deaths) and also climate - it is possible that a respiratory illness such as CV19 will have less imapct hot, wet countries than it will in cold wet countries. Hence the annual winter increase in influenza in the UK. My point here is that we cannot say that Ivermectin isn't responsible for reducing cases in countries such as India. But we need to be very cautious about saying that it is. It's the old distinction between correlation and causation. In the UK sales of ice-cream increase every summer and, at exactly the same time, we see a sudden spike in the number of drownings. But it would be wrong to conclude from these well documented facts that people were drowning because they were eating too much ice-cream.
You could also look at population density , even it hot arid countries, as a driver to transmission, many poorer countries have a dozen or more people living in a dwelling not much bigger than a large garage.
I was always under the impression that it wasnt cold winters that drove flu outbreaks but people spending more time indoors in close proximity ?
The fact is , in some situations , certain countries just never really got hit by covid very hard, the PNG example being one, also even in very tight lockdowns people still got covid, yet no flu of any description last year, despite a yearly average death toll of around 15000 for flu ?
This is merely a statement, not a challenge to your assertation.

The ice cream analogy is , like your 'people eat rice in India..' one , a bit silly .
We could say it gets hot in summer , so people die of heatstroke sometimes, did the sun make them die ?
Or, it gets hot in summer , some peopleeat ice cream and then go swimming and drown , did the heat kill them, the ice cream , or did the water drown them ?
Its fairly obvious the ice cream didnt kill them , unless the lactose intolerant have the mother of all reactions ?

I wont go over the old ground again , but 'something' bought infections and deaths down in Uttar Pradesh, and if it wasnt ivermectin , what could it have been ?
Dalua , in his wisdom , decided it wasnt ivermectin , because peer reviewed studies said it wasnt,,,,,
Don't have an answer for that one. Imagine what a boost it would be to the reputation of a research facility (and what a boost it would give to its funding streams) if it could demonstrate through peer-reviewed double-blind RCT's that a readily available out-of-patent, widely recognised and cheaply available existing drug was effective against CV19. It would be a remarkable achievement. I suspect that the reason this happened is that those who could conduct this research don't believe it lead to this result.
Read that back to yourself a few times, there are lots of interesting points in there .
Reputation.
This could work both ways , if they could prove 'one way or another' that its beneficial , or not, surely thats kudos ?
Funding.
As above , a decent study brings experience , and the possibility of future work , funding , and kudos.
One of the inventors of ivermectin even offered his uni and services to do it , and was turned down, as Ive said before, these dtudies cant possibly cost that much surely, and if its so important that we DONT take horse wormer , why dont they do these studies en masse , and put the matter to bed , instead of just TELLING people not to do it ?
Bias.
You close this statement with ' I suspect that the reason this happened is that those who could conduct this research don't believe it lead to this result'
But yet hundreds millions of people were treated with 'wormer' and continue to be , why ?
If those in academia 'know' it doesnt work , why would they continue to treat , why are they now talking about doing studies, again presumably ?
This is one point on which we do disagree. You (unvaccinated) and I (vaccinated) can both transmit the virus to others. And in fact if we both catch the virus we are equally likely to pass it on to someone else. (This isn't quite true - I might be slightly less likely to pass it on but, overall, the risk we pose to other people is we have both caught the virus is virtually equivalent). But - and this, for me, is the point - although as a vaccinated person I can still catch the virus (and I should know!) I am significantly less likely to catch it than you are as an unvaccinated person. I (vaccinated) can still catch it but you (unvaccinated) are more likely to catch it. And you can only pass on a virus if you catch it. So my reduced chances of catching it, reduce my chances of passing it on to other people.
Another interesting point , I think we can safely say that vaccine efficacy is not what it was touted to be, theoretically , the population could be 100% jabbed , and yet the disease could still continue to move around among us , indeed , making us ill , and in some cases hospitalising and killing us, is this because of the unvaccinated ? I dont believe it is.
Also what of those who have had actual covid , pre or post jab, where are the figures that show their re infection rate ?
Agree. 100%. I will be first in line protesting against a compulsory vaccination programme.
If you work in the NHS thats exactly what you now have , unless you wish to throw your career in the bin ?
 
Don’t forget that there is aye the option to do as the dear old biddys in Toronto, Fairy Hill’s headhunters in PNG, the people of Uttar Pradesh and the frontline health workers in Buenos Aires did, and elect not to risk getting the virus in the first place, whether by accident or purposely, but in either case with the use of ivermectin. If the virus isn’t in ye, you canna spread it, hence the very low incidence of daily cases where it is in widespread use, the virus needs people to breed in and pass on. The vaccines, alas, cannot prevent this, indeed they facilitate it, by dint of giving folk a false sense of security.
If we overlook the unfounded certainty with which it's written, this post contains a number of interesting hypotheses.
 
U make some good points again jason in ur reply to me, which i do agree with.

No doubt it is a roll of the dice, i'm hoping my lower exposure is allowing me to chose wether to have the jab or not ( no idea if i'm right or wrong with that)
if i lived elsewhere and my exposure was higher i might chose a different approach.
Just a risk u have to asses like every other thing in life.

To be honest i'm not really that worried about covid, i'm far far more likely to be killed or badly injured in my day job, just the risk u put up with every day u go out the door.

I must admit while hospital critical care admissions seem to be lowish there is still a hell of a positive cases goig about, it does make u wonder if these other countries are doing things better.
But while rewolf might think ur ice cream/drowning or rice secenrios are a bit silly, to be honest there not really when u are comparing apples and oranges which will often be the cases when making comparisions with other countries.

How is swedens approach getting on? Don't hear much about them now.
 
Do the previous clinical trials not show inconclusive results, or no benefit results, did you not say yourself , in your opinion ivermectin has no proven use in treating covid ?
What will you say if it does indeed prove otherwise ?
Sorry - I should have picked up this useful point earlier.

You seem to be asking whether adequate evidence of the efficacy of ivermectin in the treatment and/or prophylaxis of Covid would change my view as to its efficacy in the studied role. The answer, I hope, is obvious - of course it would: that is how we use evidence in this context.

This question again underlines the point that there seems to be a misunderstanding as to how and why people who work in this area review evidence and alter clinical practice accordingly.
 
You seem to be asking whether adequate evidence of the efficacy of ivermectin in the treatment and/or prophylaxis of Covid would change my view as to its efficacy in the studied role. The answer, I hope, is obvious - of course it would: that is how we use evidence in this context.
Not really , I asked what you will SAY, IF indeed it turns out that, after clinical trials, that are peer reviewed, show there is a place for ivermectin in the covid fighting arsenal.
How will you explain the earlier trials getting it so wrong ?
Will you examine the way you look at future drug trials, perhaps not be so dismissive of those that advocate drug repurposing ?
Like Ive said , you and the other 'experts' who ridiculed this thread and those who thought that ivermectin was worth looking at in relation to covid treatment. are now , in the light of new evidence , changing your tune.
This question again underlines the point that there seems to be a misunderstanding as to how and why people who work in this area review evidence and alter clinical practice accordingly.
In other words, you believed what you were told , now youre not so sure about it , but you were still right, because us plebs dont know how the system works ?
Theres also no issue of bias , or suppression of data, because that never happens in pharma :lol:
 
Like Ive said , you and the other 'experts' who ridiculed this thread and those who thought that ivermectin was worth looking at in relation to covid treatment. are now , in the light of new evidence , changing your tune.
I'm not aware that I've 'changed my tune'. I'm still saying what I was saying at the start, as far as I'm aware.

In other words, you believed what you were told , now youre not so sure about it , but you were still right, because us plebs dont know how the system works ?
Theres also no issue of bias , or suppression of data, because that never happens in pharma :lol:
Well, I agree with the assessment that the trials hitherto are not good enough to allow the stuff to be recommended for treatment or prophylaxis. Nothing's changed there. As for you plebs not knowing how the system works, I'm not sure - but it seems very clear that a lot of you don't get how the idea of 'evidence' in this context works. I can see that it must be frustrating when apparently really obviously-effective remedies are being overlooked - but from my perspective, I can see the the efficacy is not that obvious, and the widespread use for unproven indications not that harmless.

Having spent 30 years taking sideways views at Pharma studies, advertising etc to make sure what our patients get is prescribed by practitioners whose eyes are open, I think I have a reasonable view of how these things work; even without watching lots of YouTube videos.

Meantimes, the studies hitherto published are not very good, and their results are therefore not up to the mark to allow the stuff to be recommended for general use.

And that is where we still are.
 
I can see where the problem is, the interpretation of which can be loosely described as on the one hand ivermectin being akin to putting an apple in a sock at the bottom of the bed to cure a cold, (no evidence of efficacy), and on the other, ‘what is not looked for will not be found’ (there being no real ‘emergency’, nor willingness/incentive for finding new uses for not so profitable medicines by those whose interests do not lie primarily in the healing, or life saving but in the money-making).

Officially ivermectin may be regarded for now as being an ‘interesting placebo’ of surprising efficacy and minimal side effects in some less-developed minds and parts of the world, but perhaps not something we need here, where we have, in mRNA vaccines, something of waning and partial efficacy at best, and with an impressive number of side effects, which also require the services of the medical business.

As we were, then!
 
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Do you mean an variety or in terms of actual cases? Regardless, they are insignificant, indivudually tragic, but insignificant in terms of population health. I don't have the figures, but I suspect the side effects are also seen in those with actual Covid.

Vaccination works.

Both, though as we both know the VAERS are but a scratch of the surface.

But I agree to the extent that much like a virus that has a fatality rate that is statistically insignificant in terms of overall population health, it is tragic too for the individuals who were advised to take a vaccine which turned out to be more utterly life-changing than they may well have been led to understand.

Ivermectin works, safely, for those who use it, it seems; vaccinations of mRNA variety - still too early to tell concerning longer term impacts for the many, but time will undoubtedly tell; they do however appear to have been designed for original Covid, and as such, are rather less useful in terms of protection against delta variant - now the 97% globally distributed/encountered strain- unlike Ivermectin.

But if it 'works' and indeed continues to 'work' for you and yours, hey, that's great, we're all happy.
 
Got a guy at work …full on anti vaxxer…….I wouldn’t let the f**ker mow my lawn …..goes on about how much he knows yet I wouldn’t trust him to mix a bl00dy lemsip 😴😴😴
 
Interesting statistic: the total value of Big Pharma is widely agreed to be around 1.5 trillion USD; the total value of the alternative "wellness" industry is... (drumroll) ...4.5 trillion USD.

Even the term itself, "Big Pharma", seems laden with menace. And yet it is worth reflecting that Big Pharma is nowhere near the size of "Big Wellness". Indeed, Big Wellness is three times bigger!

What is more, the claims made by those promoting "alternative medicine" (or, perhaps, more properly "alternatives to medicine"), are not subject to anything like the levels of scrutiny faced by those in pharmaceutical industry bringing new medications to the market.

I readily accept that Ivermectin isn't an "alternative medicine". It is a product of the pharmaceutical industry every bit as much as the vaccines. However, I think the way many people argue in favour of the use of Ivermectin in respect of CV19 closely resembles the way that people argue to promote/defend the use of things which very much are alternatives to medicine - everything from healing crystals to a great many vitamin supplements (which have been repeatedly demonstrated to be of no health benefit whatsoever to people who already have a balanced diet).

It is really interesting to consider why some people are so suspicious of Big Pharma and the cause of their underlying fears - particularly in light of the readiness with which they accept alternatives that are subject to less rigorous scrutiny and supported by "evidence" that is not widely accepted.

For example, a common theme here is often how a lack of evidence in support of the alternative narrative is held up as "proof" that this evidence has been intentionally supressed by the mainstream narrative. "The shocking truth that Big Pharma doesn't want you to know..." when, in fact, it is nothing of the sort.

Another theme is the "It's my body and I'll do what I think best" argument. This is, of course, true. And that's the point: no-one is arguing against it. People should be able to do what they like with their bodies. Take Ivermectin, paint yourself blue: it makes no difference. No-one else cares - or at least no-one else should care. But the fact that someone is doing something, should not be muddled with the evidence that the thing that they are doing is a good idea.

And a third theme is control. Illness can bring with it a frightening loss of control - particularly in the context of a global pandemic. Lots of people find a loss of control very alarming and are therefore attracted to simple solutions that appear to re-assert a sense of their own agency when their automony feels threatened. "I am doing something about this - I am taking action and I am doing things my way".

...all of which explains the enormous growth of the "Wellness" industry over the course of the last 60 years. And I also think it casts a light that is worth considering in respect to our debate over Ivermectin.
 
Interesting statistic: the total value of Big Pharma is widely agreed to be around 1.5 trillion USD; the total value of the alternative "wellness" industry is... (drumroll) ...4.5 trillion USD.

Even the term itself, "Big Pharma", seems laden with menace. And yet it is worth reflecting that Big Pharma is nowhere near the size of "Big Wellness". Indeed, Big Wellness is three times bigger!

What is more, the claims made by those promoting "alternative medicine" (or, perhaps, more properly "alternatives to medicine"), are not subject to anything like the levels of scrutiny faced by those in pharmaceutical industry bringing new medications to the market.
Widely agree by who , big pharma ?
Are you seriously trying to say the GLOBAL big pharma market is 1.5 tr USD ? It wouldnt surprise me if the US market was around that figure, they spend 8-900 billion per annum on their armed forces, so to spend similar on drugs would not be a stretch.
The argument of 4.5 tr USD seemed a stretch Feeling good: The future of the $1.5 trillion wellness market
But estimating it is difficult , this is the probable source of the 4.5 tr Statistics & Facts - Global Wellness Institute

The self styled Global wellness institute , is a self promotional industry body, so hardly an unbiased source.

The main problem is though , you have tried to equate big pharma with wellness, but wellness is , as you rightly know , rarely about alternative medicine.
It encompasses gyms, yoga classes, spas , massage and supplements, yet you have tried to put these into the quack medicine pigeon hole , when they clearly are not.
Quite why you have used this as a dig at ivermectin use, when you state yourself it doesnt come under the description of 'alternative' , is mystifying.

I think what youve tried to do is this.
'Theres no wonder so many people are interested in ivermectin, given there are so many idiots out there spending good money on 'wellness'
I readily accept that Ivermectin isn't an "alternative medicine". It is a product of the pharmaceutical industry every bit as much as the vaccines. However, I think the way many people argue in favour of the use of Ivermectin in respect of CV19 closely resembles the way that people argue to promote/defend the use of things which very much are alternatives to medicine - everything from healing crystals to a great many vitamin supplements (which have been repeatedly demonstrated to be of no health benefit whatsoever to people who already have a balanced diet).
Lets be honest here , are you saying that people who are using ivermectin are just as daft as those who use crystals ?
Because thats what that sounds like, and its very very disingenuous , and highly inaccurate .

Also , who has a balanced diet these days ?
If people want to take a supplement , let them get on with it , what harm will it do ?
And , if they THINK it might help them, whats wrong with a little positive mental attitude ?
 
are you saying that people who are using ivermectin are just as daft as those who use crystals ?
Not quite. I am saying the rationale, which both groups of people appeal to in order to explain their beliefs and actions, is strikingly similar. And has similar shortcomings.

So, if you think the people who believe in healing crystals are daft, you might want to look more closely at the kinds of argument they use in order to explain their beliefs. If you do, you will find that the types of argument they appeal to are very similar to those that you use.

The content is different - obviously. But the assumptions/first princples and the line of argument that follows from them (with its emphasis on belief and the lived experience of individuals) is very similar. And similarly flawed.
 
Not quite. I am saying the rationale, which both groups of people appeal to in order to explain their beliefs and actions, is strikingly similar. And has similar shortcomings.

The content is different - obviously. But the assumptions/first princples and the line of argument that follows from them (with its emphasis on belief and the lived experience of individuals) is very similar. And similarly flawed.

Jason, youre obviously not stupid , but the rationale you have used there is absolutely flawed, and Im not sure how youve arrived at it.

Crystals, a faith based 'remedy' akin to praying for good health or a cure, the only scientific way any good result can come , is from a positive mental outlook.

ivermectin , a chemical based remedy that has proven antiviral action , but one that as yet , consensus cannot agree it has proven benefits in fighting covid, the key word being 'consensus' which it appears in this sense to be regional.
But you say the two things are similar ?

If the 'lived experience' is also similar , why are we not discussing crystal therapy in fighting covid ?
Its because no one in their right mind trusts their health to crystals , in any real application , yet millions of people trust their health to ivermectin.
Can you not see how there is no real comparison ?
 
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