Never used to use a chrono. Always shot a series of loads, starting with the minimum recommended charge, to find the most accurate group at 100m. Then I would shoot at 200 and 300m, measure the drop and use the velocity truing thingy in Shooter to arrive at a velocity estimation.
Now I have a Magnetospeed Sporter. Still find my accurate load in the same way then when I'm happy I measure 5 rounds to get my average velocity that I then use to generate my drop table. This table is then printed and taped onto the stock.
The MS does alter the POI on all of my rifles, sporters and varmints.
Cheers