Am I correct in thinking you also run a 7mm Rem mag with 120g TTSX?The correct answer here seems to depend on tolerance to two factors, degree of carcass damage and risk of runners. The two factors are largely exclusive of each other. If you use a very damaging bullet the run distance tends to be less but the carcass damage greater and vice versa. I have experienced gut penetration with Yew Tree and Virtus and also prefer the TTSX that holds together for this reason. My experience with Red and roe deer with the 6.5mm 120 grain TTSX is that the carcass is tidy but the run distance is greater. I still shoot Roe with the 6.5 but if reds are likely use the .30-06 in preference that largely mitigates the runners to an acceptable level.
